Joint Bone Spine. 2003 Aug;70(4):303-6.
Belin V, Tebib J, Vignon E.
Rheumatology Department, Lyon South Hospital Center, Lyon, France
Background. Pulmonary dysfunction in rheumatoid arthritis (RA) patients treated with low-dose methotrexate is usually caused by bacterial infection and less frequently by an immunoallergic reaction to the drug (acute hypersensitivity pneumonitis).
Opportunistic infections are a rare cause. We report a case of cytomegalovirus pneumonia during bone marrow aplasia in a patient with RA taking methotrexate and cyclosporine.
Conclusions. – Cytomegalovirus infection is a rarely reported cause of pulmonary dysfunction. This diagnosis should be considered in immunocompromised RA patients with no other satisfactory explanation for pulmonary dysfunction.
PMID: 12951317 [PubMed – in process]