Abstract: Cytomegalovirus infection in a patient with rheumatoid arthritis

Joint Bone Spine. 2003 Aug;70(4):303-6.

Belin V, Tebib J, Vignon E.

Rheumatology Department, Lyon South Hospital Center, Lyon, France

Background. Pulmonary dysfunction in rheumatoid arthritis (RA) patients treated with low-dose methotrexate is usually caused by bacterial infection and less frequently by an immunoallergic reaction to the drug (acute hypersensitivity pneumonitis).

Opportunistic infections are a rare cause. We report a case of cytomegalovirus pneumonia during bone marrow aplasia in a patient with RA taking methotrexate and cyclosporine.

Conclusions. – Cytomegalovirus infection is a rarely reported cause of pulmonary dysfunction. This diagnosis should be considered in immunocompromised RA patients with no other satisfactory explanation for pulmonary dysfunction.

PMID: 12951317 [PubMed – in process]

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