Abstract: Depressed mood impedes pain treatment response in patients with fibromyalgia

J Rheumatol. 2004 May;31(5):976-80. Finset A, Wigers SH, Gotestam KG. Department of Behavioural Sciences in Medicine, University of Oslo, Oslo, Norway.

OBJECTIVE: To investigate prognostic factors in the course of the fibromyalgia syndrome (FM) from baseline to post-treatment.

METHODS: Fifty-seven patients with FM were examined in a randomized intervention study. Pre-treatment variables were entered into linear regression analyses: gender, age, duration of disease, allocation to treatment, pain distribution (based on a patient-made drawing), fatigue, sleep disturbance, and depressed mood (based on visual analog scores), with pain distribution at treatment completion as the dependent variable.

RESULTS: Depressed mood at baseline was a significant predictor of sustained widespread pain at treatment completion.

CONCLUSION: The findings indicate a role for depressed mood as a predictive factor for treatment response.

PMID: 15124260 [PubMed – in process]

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