Abstract: Lessons from a pilot study of transfer factor in Chronic Fatigue Syndrome (CFS)

De Vinci C, Levine PH, Pizza G, Fudenberg HH, Orens P, Pearson G, Viza D

Transfer Factor (TF) was used in a placebo controlled pilot study of 20 patients with chronic fatigue syndrome (CFS). Efficacy of the treatment was evaluated by clinical monitoring and testing for antibodies to Epstein-Barr virus (EBV) and human herpes virus-6 (HHV-6). Of the 20 patients in the placebo-controlled trial, improvement was observed in 12 patients, generally within 3-6 weeks of beginning treatment. Herpes virus serology seldom correlated with clinical response. This study provided experience with oral TF, useful in designing a larger placebo-controlled clinical trial.

Source: International Transfer Factor Society

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