Lancet. 2004 Jan 24;363(9405):291-2.
Klein GL, Chen TC, Holick MF, Langman CB, Price H, Celis MM, Herndon DN.
Department of Paediatrics, University of Texas Medical Branch, Galveston TX 77555-0352, USA. email@example.com
Severe burn injury is associated with vitamin D deficiency, low bone turnover, and abnormalities in calcium homoeostasis. Patients do not routinely receive vitamin D supplementation and sun exposure is currently not controlled. By analysis of skin biopsy samples for vitamin D3 precursors after exposure to ultraviolet B light we found that the conversion of 7-dehydrocholesterol to previtamin D3 was reduced in children a mean of 14 months after the burn. Low serum 25-hydroxyvitamin D concentrations were also found. We conclude that vitamin D supplementation is necessary after burn injury.
PMID: 14751703 [PubMed – in process]