Likholetov SM, Prokof’eva EI, Rogozhkina NM
Experiments conducted on non-linear mice demonstrated a possibility of transfer by the intact recipient of delayed hypersensitivity by means of Lawrence’s transfer-factor from mice immunized with Coccidioides immitis. The transfer factor administered 48 hours before the intranasal infection protected mice from the lethal dose of coccidioides. This indicated that in coccidioidosis it was possible to transfer delayed hypersensitivity and cellular immunity with the transfer factor.
Zh Mikrobiol Epidemiol Immunobiol 1978 Sep;(9):60-4
PMID: 747028, UI: 79141688