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Based on a survey of hunter-harvested deer, the suspected primary vector of
Lyme disease in the Southeast, I. scapularis, is most prevalent in sandhill and coastal plain counties of South Carolina. None of 271 I. scapularis examined were found to be infected with the
Lyme disease spirochete. However, many more specimens of I. scapularis, A. americanum, and other tick species must be examined before an accurate estimate of the probability of acquiring
Lyme disease in South Carolina can be made.