Antimuscle & anti-CNS circulating antibodies in Chronic Fatigue Syndrome (CFS)

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Chronic fatigue syndrome (CFS) patients suffer from disabling
physical and mental fatigue. Circulating autoimmune antibodies
may produce symptoms of muscular fatigue by reacting with
acetylcholine receptors or calcium binding channels. They can
also produce mental status changes by reacting with central
nervous system (CNS) antigens. We thoroughly investigated the
presence of circulating antimuscle and anti-CNS antibodies in
10 CFS patients and 10 controls. We were unable to detect any
pathogenic antibodies.

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