Beneficial effects of resveratrol on atherosclerosis – Source: Journal of Medicinal Food, Dec 2008

[Note: Resveratrol is a naturally-occurring compound found most abundantly in the skin of red grapes, berries, red wine, peanuts, and the root of a flowering plant used in traditional Chinese medicine – Polygonum cuspidatum.]

Atherosclerosis, a progressive disease characterized by the accumulation of lipids and fibrous elements in the arteries, is a most important contributor to cardiovascular diseases. Resveratrol is a naturally occurring phytopolyphenol compound, and shows the ability to reduce the risk of cardiovascular diseases.

In this review, beneficial effects of resveratrol on the initiation and progression of atherosclerosis – including:

• Regulation of vasodilator and vasoconstrictor production [blood pressure],

• Inhibition of oxidative stress/reactive oxygen species generation,

• Anti-inflammation,

• Inhibition of modification of low-density lipoproteins [“bad” cholesterol],

• Anti-platelet aggregation [anti-clotting],

• And its abilities to impede progression and modulate complications of atherosclerosis
– are discussed.

Source: Journal of Medicinal Food, Dec 2008;11(4):pp610-614. PMID: 19053850, by Fan E, Zhang L, Jiang S, Bai Y. College of Life Sciences, Nankai University, Tian Jin, People’s Republic of China; Institute of Plant and Cell Physiology, Martin-Luther University, Halle/Saale, Germany; [E-mail: Enguo Fan,]

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