A team of researchers in Germany compared the time of responses in the central nervous system between 181 CFS patients and a group of controls. They found significantly slower nerve impulses in CFS patients, which they said provided evidence for the possibility of a neurological disorder that could be any of several types of nerve degeneration. However, the procedure they used, magnetic stimulation, was not sufficient to identify a specific nerve problem such as demyelinization. These researchers also note the similarities of their findings in CFS to those found in multiple sclerosis and a number of other diseases, and they raise the question whether “CFS can be considered as a disease on its own or whether it might be more a syndrome associated with early stages or manifestations of many chronic diseases.”
Hilgers, A., Frank, J., and Bolte, P. (1998). Prolongation of central motor conduction time in chronic fatigue syndrome. Journal of Chronic Fatigue Syndrome, 4:2, 23–32.