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CFS Treatment Overview; 3 Subgroups in FM?; New RNase L Research

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FEATURE ARTICLES – October 22, 2003:

* Chronic Fatigue Syndrome: “What Should I Know, How is it Treated?”

* Study Identifies Three Distinct Subgroups of Fibromyalgia

* RNase L in Health and Disease: What Did We Learn Recently?


* Guaifenesin


* Support and Inspiration in the Coping Corner

* Got Questions? Here are Answers…Find them in our Chat Room


* NJCFSA Fall Conference


* Webmaster Tools & Link Exchange Programs


* Refer a Friend

* Not a Subscriber?

* About Us

See below for links. Either click on any active (i.e., underlined) link, or copy and paste the link into your Internet browser (i.e., Explorer, Netscape, AOL, CompuServe).

Feature Articles

* Chronic Fatigue Syndrome: “What Should I Know, How is it Treated?”

“Chronic fatigue syndrome is the current name for a disease that has been described for three centuries. It is characterized by a debilitating fatigue and a variety of other physical, constitutional, and neuropsychological complaints. Certain individuals, who were labeled in the past with various diagnoses ranging from neurasthenia to encephalomyelitis, are now thought to have chronic fatigue syndrome.” Here is an overview of some treatment options.

* Study Identifies Three Distinct Subgroups of Fibromyalgia

Researchers believe they have identified three distinct subgroups of patients with fibromyalgia (FM), according to results published in the October 2003 issue of Arthritis & Rheumatism. These distinctions could help lead to more targeted therapies.

* RNase L in Health and Disease: What Did We Learn Recently?

Patrick Englebienne is affiliated with the Department of Nuclear Medicine at the Free University of Brussels in Belgium. Of his research into RNase L, he states, “our understanding of the origin and consequences of the RNase L deregulation in chronic fatigue syndrome offers the opportunity to fully appreciate the value of the truncated form as a biochemical marker, the detection of which allows for the implementation and follow-up of new possible therapeutic interventions.”


According to Devin Starlanyl, Ph.D., “Excess calcium and inorganic phosphate can cause mitochondrial hyperpermeability. This will allow excess fluids, ions and other substances into the mitochondria that don’t belong there, producing swelling and interfering with normal function. This may be part of what happens in fibromyalgia (FM).

Dr. R. Paul St. Amand believes FM is caused by an abnormality in phosphate excretion, which may be due to a genetic defect. Retention of phosphates eventually interferes with energy production in the affected cells.

One study found a 20 percent reduction in the level of ATP in muscle biopsies taken from people with FM. Excess inorganic phosphate in the mitochondria, your energy-generating cells, slows formation of ATP. Muscle pain after exercise is also linked with an increase in inorganic phosphate.

Guaifenesin is an ingredient found in cold preparations. In its original form, as a tree bark extract called guaiacum, it was used to treat rheumatism in the 16th century. In the Physicians’ Desk Reference for Herbal Medicines, guaiacum officinale is indicated for rheumatism. Over twenty years ago it was synthesized, named guaifenesin, and pressed into tablets. Using guaifenesin therapy, Dr. St. Amand found a 60 percent increase in phosphate excretion and a 30 percent increase in oxalate in his patients’ urine.” To read more about guaifenesin, click on the link below:

Support and Inspiration in the Coping Corner!

Dealing with the day-to-day struggles of living with a chronic illness can be trying. Coping Corner is the spot where you can find the online support you need to get through your day. Featuring personal stories, advice columnist Eunice Beck, RN, book reviews, and more.

Got Questions? Here Are Answers…

Need a specialist in your location? Not sure what sleep meds are the best? Don’t know how to deal with the spouse, kids, and dog? Who better to help you than your fellow readers at When you post a question to the message board, you can be assured of speedy and helpful replies. Other people have been through the same struggles and are happy to share their wisdom. It’s easy, too!

If you’re feeling chattier, go to the chat room and ‘talk’ to others in real time. You can let people know when you’ll be there by posting a note to the message boards.

Just click on the link below to find friends and support in the message boards and chat room:

NJCFSA Fall Conference

The NJCFSA Fall Conference will take place on Sunday November 2, 2003, at the Sheraton Conference Center in Eatontown, New Jersey.

The conference program is “New Directions in Research and Therapy in Chronic Fatigue Syndrome” and Kenny De Meirleir, M.D., Ph.D., will be one of the guest speakers. For more information including the complete program schedule and how to register, click on the following link: Webmaster Tools & Link Exchange Programs

Pro Health is proud to offer CFS & FM Webmaster Tools & Link Exchange Programs at! We have designed these features to enable CFS & FM sites all over the world to get connected so we can work together to share important information and resources with our readers.

We invite webmasters to post headlines for the latest CFS & FM treatments and breaking news on your websites (linking to the complete content), in addition to linking to CFS & FM events, chat forums and message boards. We also invite CFS and FM related websites to link with us. To learn more about these programs, click on the link below:

Refer a Friend!

Do you have a friend or relative who would find the information in this bulletin useful? All you need to do is click on the link below, or forward this email to them, and they can begin reading all the latest CFS and FM research and support news.

Not a Subscriber?

Don’t miss out! If you are not currently subscribed to this bulletin or any of our other informative treatment & research email bulletins – along with our very helpful “Tip of the Day” emails, simply click on the link below to sign up today – it’s free!:


Published by Pro Health, Inc., is the Web’s largest resource for Chronic Fatigue Syndrome and fibromyalgia. Since 1988, Pro Health has raised and donated over 2.3 million dollars to CFS and FM research and advocacy groups seeking a cure. Every purchase made at funds research – as does every purchase made from Pro Health’s Health Resource catalog. Click on this link to visit’s home page:

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