Chronic fatigue: a peculiar evolution of eosinophilia myalgia syndrome following Rx w L-tryptophan in 4 Italian adolescents

We describe four Italian adolescents in whom a persistent,

debilitating fatigue appeared after therapeutic ingestion of

products containing L-tryptophan and subsequent to the

development of a transient rise in eosinophil count and severe

myalgia (Eosinophilia Myalgia Syndrome-EMS). Their clinical

picture was indistinguishable from that of the so-called

Chronic Fatigue Syndrome. A chronic fatigue may occur after

diverse triggering agents and its represents the peculiar

clinical evolution of these four paediatric cases of EMS.

Priori R, Conti F, Luan FL, Arpino C, Valesini G

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