Cognitive Dysfunction in Fibromyalgia and Chronic Fatigue Syndrome: New Trends and Future Directions

Journal: Current Rheumatology Reports. 2006 December; 8(6):425-429. Author and affiliation: Jennifer M. Glass. University of Michigan, Institute for Social Research and Department of Psychiatry, 426 Thompson Street, Room 5256, Ann Arbor, Michigan, 48106-1248, USA. PMID: 17092441

Fibromyalgia (FM) and Chronic Fatigue Syndrome (CFS) patients often have memory and cognitive complaints. Objective cognitive testing demonstrates long-term and working memory impairments. In addition, CFS patients have slow information-processing, and FM patients have impaired control of attention, perhaps due to chronic pain.

Neuroimaging studies demonstrate cerebral abnormalities and a pattern of increased neural recruitment during cognitive tasks. Future work should focus on the specific neurocognitive systems involved in cognitive dysfunction in each syndrome.

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