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Complement fixation test for the diagnosis of Lyme disease.

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Abstract

Sera from 43 patients were tested for complement-fixing antibodies to Borrelia burgdorferi; these patients included 8 with confirmed
Lyme disease, 21 who were serologically positive but not likely to have
Lyme disease, and 14 who were serologically negative. Seven individuals, all confirmed
Lyme disease patients, had complement-fixing antibodies. Complement fixation may be a useful confirmatory test for
Lyme disease.

J Clin Microbiol. 1990 Mar;28(3):637-8.

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