Demyelinating encephalopathy in Lyme disease.


A 38-year-old man from southeastern Connecticut developed a diffuse encephalopathy with partial complex seizures, followed weeks later by arthritis, cryoglobulinemia, and increased serum IgM. CT showed confluent low-density lesions in the deep cerebral white matter consistent with demyelination. Neither the encephalopathy nor the CT abnormalities improved.
Lyme disease was diagnosed serologically 4 years later.

Neurology. 1985 Feb;35(2):267-9. Case Reports

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