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To evaluate the diagnostic usefulness of routine
Lyme serology in patients who live in nonendemic areas and present with early inflammatory joint
All patients admitted to a rheumatology department of a nonendemic area of France for evaluation of joint
disease with onset within the last year. The evaluation included a medical history, a thorough physical examination, an electrocardiogram, and an ELISA for antibodies to Borrelia burgdorferi.
We included 90 patients, 51 women and 39 men, with a mean age of 48.1 +/- 17.9 years. Mean duration of joint symptoms was 4.3 +/- 4.3 months, with a median of 3 months. A patient (1.1%) reported a tick bite and no patients had a history of erythema migrans.
Lyme serology was negative in all 90 patients.
These results do not support routine
Lyme serology in patients living in nonendemic areas and presenting with early inflammatory joint
Lyme serology remains appropriate in patients with features suggestive of
Lyme disease. Given that
Lyme disease is amenable to curative treatment, a larger study is in order to confirm our findings.