Dietary calcium and magnesium intakes and the risk of type 2 diabetes: The Shanghai Women’s Health Study – Source: American Journal of Clinical Nutrition, Apr 2009

Background: Diet plays a key role in the development of type 2 diabetes (T2D), but little is known about the contributions of specific nutrients in populations in which dietary patterns differ from Western populations.

Objective: We examined associations between calcium and magnesium intakes and the risk of type 2 diabetes in a Chinese population.

Design: We used data from a population-based, prospective study of 64,191 women who were free of type 2 diabetes or other chronic diseases at study recruitment and were living in urban Shanghai, China. Dietary intake, physical activity, and anthropometric measurements were assessed through in-person interviews. A Cox regression model was used to evaluate the association of the exposures under study with the risk of type 2 diabetes.

Results: An inverse association between calcium and magnesium intakes and type 2 diabetes risk was observed. The relative risks for the lowest to the highest quintiles of calcium intake were 1.00, 0.82, 0.73, 0.67, and 0.74 (P for trend < 0.001), and for magnesium they were 1.00, 0.84, 0.84, 0.79, and 0.86 (P for trend < 0.001).

Milk intake was also inversely associated with the risk of type 2 diabetes.

Conclusion: Our data suggest that calcium and magnesium intakes may protect against the development of type 2 diabetes in this population.

Source: American Journal of Clinical Nutrition, Apr 2009; 89:1059-1067. PMID: 19225116 Villegas R, Gao YT, Dai Q, Yang G, Cai H, Li H, Zheng W, Shu XO. Vanderbilt Epidemiology Center, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, USA. [E-mail: raquel.villegas@vanderbilt.edu]

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