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Duration of treatment for Lyme borreliosis: time for a critical reappraisal.

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Abstract

Over time the recommended duration of antibiotic therapy for patients with erythema migrans has increased. This change in prescribing practice is not evidence-based. The presumptions that post-treatment subjective complaints, which occur in a minority of patients, may be reduced by increasing the duration of initial therapy or ameliorated by a repeat course of parenteral or oral antimicrobials, have not been supported by recent clinical trials. Recommendations on duration of treatment of early
Lyme borreliosis deserve critical reappraisal.

Wien Klin Wochenschr. 2002 Jul 31;114(13-14):613-5. Review

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