Evaluation of costs in rheumatic diseases: a literature review – fibromyalgia related research

The aim of our review was to examine recently published cost-

evaluations presenting originally developed data in rheumatic

conditions. We identified 21 articles: 9 presenting original

data on rheumatoid arthritis and/or osteoarthritis; 7 focusing

on other musculoskeletal conditions such as back pain,

scleroderma, Lyme disease, and fibromyalgia; and 5 assessing

costs in total knee and hip arthroplasty. Most of the studies

originated in the United States. In contrast to earlier

reviews in this journal, fewer studies focused on only

pharmacoeconomic aspects. In reviewing these studies, we found

a lack of standardization in cost-assessment leading to a

limited comparability of study results. As main tasks to

improve the evidence achieved by performing cost-evaluations

in clinical settings, we identified a standardization of main

cost-components that should be covered by each clinical trial

and the assessment of validity, reliability, and comparability

of different data sources used to collect cost-data.

Ruof J, Hulsemann JL, Stucki G

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