Fibromyalgia (FM) is not a muscle disorder

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Originally described as “fibrositis,” fibromyalgia has long

been considered a muscle disorder, and many studies have

investigated the possible pathologic basis of the disorder by

examining muscle tissue, using various methodologic

approaches. Although initial studies suggested a possible

pathologic basis in muscle, most had serious methodologic

limitations. More recent studies, however, have avoided

methodologic pitfalls and indicate that the muscles of

patients with fibromyalgia are normal. When data from studies

of tenderness are also taken into account, the weight of

evidence suggests that fibromyalgia is a chronic pain syndrome

which has a central rather than peripheral or muscular basis.

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