Fibromyalgia syndrome (FM) & nonarticular tenderness in relatives of patients with FM

nonarticular tenderness in relatives of patients with FM.
Thirty female patients with FM randomly chosen from 117 of
their close relatives (parents, brothers, sisters, children,
husbands) were assessed for nonarticular tenderness. A count
of 18 tender points was conducted by thumb palpation, and
tenderness thresholds were assessed by dolorimetry at 9 tender
sites. FM was diagnosed according to the 1990 American College
of Rheumatology criteria.
RESULTS: The prevalence of FM among
blood relatives of patients with FM was 26%, and among their
husbands 19%. FM prevalence in male relatives was 14%, and in
female relatives 41%. The mean tender point counts of male and
female young relatives was significantly higher than that of
controls: 6.1 vs 0.2 (p < 0.01), and 4.4 vs 0.4 (p < 0.01)
respectively. Similarly, adult relatives had considerably
higher mean tender point counts than controls: 4.0 vs 0.04 (p
< 0.01) and 10.3 vs 0.28 (p < 0.01) respectively, for males
and females.
CONCLUSION: Relatives of patients with FM have a
higher prevalence of FM and are more tender than the general
population, as recently reported and shown in a healthy
control group. This finding can be attributed to genetic and
environmental factors.

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