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Granulomatous thrombophlebitis in Lyme borreliosis–case report.

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Abstract

The presented case report shows a patient with
Lyme disease who also developed thrombophlebitis saltans. Histopathologically we found a granulomatous perivasculitis, an immunohistological investigation showed deposits of IgG, IgA, IgM, C3 and C4 in the vessels. Antibody titers against Borrelia burgdorferi were elevated, but no anti-cardiolipin antibodies were found. A pathogenetic correlation due to anti-phospholipid antibodies that have been found in thrombosis and borreliosis or a vasculitis vasorum comparable to a previously described vasculitis nervorum might be discussed.

Immun Infekt. 1990 Apr;18(2):57-8. Case Reports; English Abstract

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