BACKGROUND: Fibromyalgia is not an uncommon condition. Because its
cause has yet to be identified. treatment of the condition has
been empirical; frequently, outcomes are unsatisfactory. Some
patients with fibromyalgia were observed to have high hair
calcium and magnesium levels compared with healthy subjects.
Because of this and because supplementing calcium with
magnesium to fibromyalgia subjects reduced the number of
tender points detected by digital palpation, it is worth
investigating if patients with fibromyalgia have significantly
higher hair calcium and magnesium levels than their healthy
OBJECTIVES: To determine the degree of
difference between the hair calcium and magnesium levels in
patients with fibromyalgia and in healthy subjects.
The study was retrospective and of paired design. Twelve
patients who had hair analysis performed and met the criteria
of fibromyalgia defined by American College of Rheumatology
(1990) were selected consecutively from clinical files. These
patients were then matched by age and sex to 12 healthy
subjects selected consecutively from the same patient files
who had hair analysis performed for checkup purposes.
Nonparametric Wilcoxon rank sum tests were used to determine
if the hair calcium and magnesium levels in patients with
fibromyalgia were significantly higher than that of the
RESULTS: Wilcoxon rank sum tests showed that
patients with fibromyalgia had significantly higher calcium
and magnesium levels than the control subjects at alpha = .025
and .05, respectively.
CONCLUSION: In the presence of high
hair calcium and magnesium levels, calcium and magnesium
supplements may be indicated as an adjunctive treatment of