Reprinted with the kind permission of Life Extension.
November 11 2016. On November 10, 2016 in JAMA Oncology reported the outcome of a study conducted by researchers from Kaiser Permanente and Roswell Park Cancer Institute which found improved overall survival in breast cancer patients whose serum vitamin D levels were highest.
Subscribe to the World's Most Popular Newsletter (it's free!)
The study included 1,666 women with invasive breast cancer who enrolled in the Pathways Study of breast cancer survivors beginning in 2006. Blood samples collected after diagnosis were analyzed for serum 25-hydroxyvitamin D. Follow-ups conducted at 12, 24, 48, 72 and 96 months provided information on health outcomes.
"With the extremely rich data sources from a large sample size, we were able to prospectively analyze three major breast cancer outcomes — recurrence, second primary cancer and death," noted lead author Song Yao, PhD, of the Roswell Park Cancer Institute. "We were also able to adjust for multiple possible contributing factors that could influence vitamin D levels, such as age, obesity, race and ethnicity, socioeconomic status, and several tumor characteristics that are known to influence breast cancer outcomes — to ensure that the effects we observed were independent of these factors.”
"We found that women with the highest levels of vitamin D levels had about a 30 percent better likelihood of survival than women with the lowest levels of vitamin D," reported lead investigator Lawrence H. Kushi, ScD, of the Kaiser Permanente Northern California Division of Research." The effect was even stronger among premenopausal women.
"The more we know about vitamin D, the more we understand that it may play a key role in cancer prevention and prognosis," Dr. Kushi added. “This study adds to the evidence that vitamin D is an important nutrient."