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HLA-DR in meningopolyneuritis of Garin-Bujadoux-Bannwarth: contrast to Lyme disease?

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Abstract

Sixteen patients with meningopolyneuritis of Garin-Bujadoux-Bannwarth (MPN-GBB) were examined for HLA-DR antigens. In contrast to data in
Lyme disease (LD), which is caused by an identical or closely related spirochete, no significant association was found between the neurological
disease and HLA-DR. The reported association between neurological
disease and HLA-DR2 in LD may be due to the inclusion of cases with neurological
disease and arthritis, since chronic arthritis in LD seems to be well correlated with HLA-DR2.

J Neurol. 1984;231(5):271-2. Comparative Study

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