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In vitro assessment of antiborrelial activity of OspA vaccine sera.

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Abstract

Prevention of
Lyme disease by the recombinant OspA-based vaccine reportedly works by preventing transmission of spirochetes from ticks to humans. We report on an in vitro microculture assay, which can be used to provide an indicator of the need for booster doses of vaccine.

Clin Diagn Lab Immunol. 2002 Jul;9(4):919-20. Comparative Study

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