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Infection in rabbits with the Lyme disease spirochete.

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Abstract

Of 33 rabbits inoculated with
Lyme disease spirochetes, two developed erythema chronicum migrans at the site of inoculation. Spirochetes were seen in skin biopsies of one of the lesions with immunoperoxidase and Warthin-Starry stains. Spirochetes were also recovered from the blood of two additional rabbits two weeks post-inoculation. These findings are characteristic of early
Lyme disease in humans.

Yale J Biol Med. 1984 Jul-Aug;57(4):613-6. Research Support, Non-U.S. Gov’t; Research Support, U.S. Gov’t, P.H.S.

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