Interstitial cystitis: unexplained associations with other chronic disease & pain syndromes

OBJECTIVE: To determine the prevalence of concomitant disease

in individuals with interstitial cystitis and to compare these

results to the general population.

METHODS: We used a

questionnaire-based study evaluating 12 disease processes and

a survey of interstitial cystitis characteristics. The

population was 2,405 individuals with interstitial cystitis

who responded to the initial survey and an additional 277

individuals who were randomly selected and individually


RESULTS: Allergies, irritable bowel syndrome, and

sensitive skin were the most common diseases in the

interstitial cystitis population. In comparison to the

general population, individuals with interstitial cystitis

are 100 times more likely to have inflammatory bowel disease

and 30 times more likely to have systemic lupus

erythematosus. In addition, allergies, irritable bowel

syndrome, sensitive skin, and fibromyalgia have an increased

association with interstitial cystitis.


Interstitial cystitis has, as yet, an unexplained association

with certain other chronic disease and pain syndromes.

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