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Is Fibromyalgia a Mitochondrial Disorder?

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Reprinted with the kind permission of Cort Johnson and Health Rising.

We tend to think of fibromyalgia as a central nervous system disease but that focus has tended to obscure the growing evidence of problems in the body.

We don’t tend to think of fibromyalgia as an inflammatory disorder. It’s true that overt signs of inflammation are rarely found in people with FM, but some studies suggest inflammatory factors may play a role.

Then there are the mitochondria. Mitochondrial dysfunction is thought of as a real possibility in chronic fatigue syndrome, but I’ve rarely associated it with fibromyalgia or pain. It turns out, however, that multiple studies – most of them small – suggest that mitochondrial dysfunction could indeed play a significant role in fibromyalgia.

Could fibromyalgia, whatever else it is – also be a mitochondrial disorder?

A Mitochondrial Disorder?

Studies suggest the energy factories may be running a bit low in FM. Muscle biopsies have found patterns of mitochondrial dysfunction (abnormal mitochondria, mitochondrial defects and muscle fiber abnormalities) similar to those typically found in mitochondrial disorders. Some skin biopsies have shown patterns of neurogenic inflammation and oxidative stress – two factors that negatively impact the mitochondria. Peripheral blood cells have demonstrated CoQ10 deficiency, mitochondrial dysfunction, oxidative stress and mitochondrial degradation.

In 2013 a Spanish group proposed that mitochondrial dysfunction in FM patients was driving an inflammatory process. Now, in 2015 they have returned with a study looking at mitochondrial dysfunction, oxidative stress and inflammation using skin biopsies from people with FM.

Given the allodynia present and the increasing evidence of small fiber neuropathy in FM, the skin is becoming an ever more intriguing place to look in fibromyalgia. Something, after all, is “burning away” those small unmyelinated nerve fibers in their skin. Is it inflammation? Are the mitochondria going bananas? (Could it be both?) This study won’t tell us what’s causing the SFN or allodynia in FM – it’s not going to assess either of them – but it may provide some suspects future studies can follow up on.

This small Spanish study looked at the levels of mitochondrial enzymes, mitochondrial proteins, ATP, CoQ 10 and TNF-a from a small patch of skin in the left shoulder region, as well as in the blood and saliva of 23 people with FM and 20 healthy controls.

A Mitochondrial Disorder

Significant reductions in mitochondrial enzyme activity (in complexes I, II, III and IV) were found in the FM patients but not the healthy controls. That, in combination with reduced levels of mitochondrial proteins, indicated that mitochondrial functioning was indeed significantly reduced. So were CoQ10 and ATP levels and mitochondrial DNA levels. In fact, every aspect of mitochondrial functioning tested was found to have taken a significant hit in the FM patients.

That suggested mitochondrial damage had occurred and that finding set the stage for the next test. Since damaged mitochondrial DNA are known to spark an inflammatory response, the researchers asserted they should also be able to find evidence of inflammation in the skin – and they did. Double the levels of the pro-inflammatory cytokine TNF-a were found in the skin of the FM patients.

Not only were the increased cytokine levels strongly associated with reduced mtDNA – suggesting that the mitochondrial problems had indeed sparked the inflammation – but they were highly correlated with the pain levels in FM (p<.001) as well. That suggested the mitochondrial problems could be causing or contributing to the pain the FM patients were experiencing.

A threefold increase in TNF-a levels in the saliva and the blood collected from the biopsy area relative to the healthy controls suggested that widespread or systemic inflammation and oxidative stress was present as well. The FM patients looked pretty much like a soup of mitochondrial dysfunction, oxidative stress and inflammation.

The Pain, Inflammation and….Mitochondrial Disorders?

They are not alone. A similar situation appears to apply in diabetic patients with peripheral neuropathy and/or allodynia. Low levels of mitochondria have also been associated with small fiber neuropathy – a condition that appears to occur in about 40% of people with fibromyalgia.

Cancer associated pain displays some similarities as well. The sensory and autonomic nerves appear to be primarily affected in both cancer pain and FM. Pro-inflammatory cytokines, oxidative stress, mitochondrial damage/dysfunction, dorsal root ganglia, central sensitization, immune activation, and possibly microglial activation have been implicated in both as well.

Some models of cancer pain mimic the pain model proposed in this paper – mitochondrial dysfunction sparking an innate immune response that ends up damaging the peripheral nerves.

Cancer pain researchers are looking at novel treatments to undo this mitochondrial/inflammatory mess. They include ways to block peroxynitrite and heat shock proteins, using minocycline, an antibiotic, to attenuate activated microglia, and adenosine receptor agonists to protect the nerves. If mitochondrial dysfunction does induce pain in cancer, any of the above could ultimately show up as a treatment option for FM patients.

Chicken or the Egg?

Whether mitochondrial dysfunction is causing inflammation or inflammation is knocking out the mitochondria is unclear, however. The fact that anti-inflammatory drugs have not generally been found to be particularly effective in FM argues against an inflammatory origin. (The right types of anti-inflammatories, however, may not have been tested. )

Several studies, on the other hand, suggest that mitochondrial enhancers such as CoQ10 may be helpful in reducing the pain and headache symptoms in FM, and some practitioners have had good results with D-Ribose in ME/CFS and/or FM.

CoQ10 is a particularly intriguing nutrient given its ability to both boost ATP production and reduce levels of oxidative stress. C0Q10 levels are reportedly low in many neurodegenerative disorders including Parkinson’s disease, diabetes, fibromyalgia and cancer.

A fibromyalgia study by this Spanish research group found a 50% reduction in COQ10 levels in FM. With dozens of mostly small studies examining mitochondrial dysfunction and CoQ10 levels/supplementation in FM and other disorders under it’s belt, this Spanish research group has been leading the way in this area.

On the ME/CFS side, Maes has been producing review papers and studies on oxidative stress, mitochondrial functioning and inflammation for years. Presentations on the exercise problems in ME/CFS at the IACFS/ME Conference also appeared to be pointing an arrow at the mitochondria.

Interest in the mitochondria appears to be, er, powering up. Dr. Klimas’s Institute of Neuro Immune Medicine at Nova Southeastern University recently engaged a mitochondrial expert. The Chronic Fatigue Initiative’s announcement that they’re going to be digging into the mitochondria suggests we may get some much-needed high-powered studies into the field.

The results of one such study – the multi-center Synergy trial in chronic fatigue syndrome – that’s been testing the effectiveness of a low-dose stimulant in combination with mitochondrial and immune enhancing supplements in ME/CFS – should be out around mid-year.

Stay tuned.


About the Author: Cort Johnson has had ME/CFS for over 30 years. The founder of Phoenix Rising and Health Rising, Cort has contributed hundreds of blogs on chronic fatigue syndrome, fibromyalgia and their allied disorders over the past 10 years. Find more of Cort’s and other bloggers’ work at Health Rising.

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18 thoughts on “Is Fibromyalgia a Mitochondrial Disorder?”

  1. ProHealth-Editor says:

    I’ve long thought FM was a mitochondrial disorder. Then something happened in my family that has convinced me that, for me at least, it definitely is.

    A few years ago, my grandson began having seizures. He was ultimately diagnosed with a mitochondrial disorder. When my daughter and her husband took him to a mitochondrial specialist, they were given a pamphlet about mitochondrial disorders. In the pamphlet, it mentioned that what is diagnosed as FM and ME/CFS is often actually a form of mitochondrial disorder. When she read the symptoms of MD, she called me and said, “Mom, this sounds like you!”

    We then learned that what he has is hereditary and is only passed on through the females, which means I had to have passed it on to my daughter, then to him. Apparently it doesn’t show up in every generation and the males can be affected even though they can’t pass it on. While I don’t have absolute proof that his MD and my FM are connected, it sure does seem like they would be. I’m planning to have a test done to see if he and I have the same genetic mutation.

    Thankfully, my grandson is doing very well now and hasn’t had a seizure in four years. They started him on CoQ10, L-carnitine and vitamins C and E right away as well as three anti-seizure medications. Now he’s down to one anti-seizure medication and the supplements – and they’re going to start tapering him off the last medication soon. His doctors think the CoQ10 is making the difference for him.

    When his doctor first prescribed the CoQ10, my daughter suggested I try it, too. I did and it made a significant difference in my energy level. I still take the CoQ10 and recently added PQQ, which is supposed to boost CoQ10 and has been found to actually generate new mitochondria. Between those and the high-dose thiamine, my energy levels are better than I ever thought possible!

  2. celiamarie says:

    I have fibro & am taking CoQ10. What is the correct dosage? What is PQQ?

    1. IanH says:

      PQQ (pyrolle-quinoline quinone) is flavine quinone.
      It is sometimes called vitamin P because it cannot be made in the body but is essential. It comes in many foods but in very small quantities. The highest being in Nato (a Japanese fermented tofu), Parsley and Kiwi fruit and Green Tea.

      It is an antioxidant and has anti-inflammatory action. It also stimulates mitochondrial genesis, lifting the number of mitochondria within most cells including in the brain and spinal nerves.

      Like CoQ10 it is a co-factor in many reactions particularly those involving the dehydrogenases.

      the levels of free PQQ in human tissues or body fluids are 0.8-5.9 ng/ml. There is some evidence that our enteric bacteria do not synthesize PQQ for us so we must get it from our diet (a true vitamin).

      Research into this vitamin is in its infancy but its deficiency is proving to be a likely problem because of our diet. The level in the body as quoted above is no indicator of the bodies requirement, that is not known. In all likelihood it will be like vitamin D where typical level is 12ng/ml to 20ng/ml but the required level is around 40ng/ml, more if you are ill.

  3. CookieB says:

    I have been getting a rash for about 3 yrs now ,was just found that I had Fibro 1 1/2 years ago.The rash seems to come and go and appears all over very itchy.No one can tell me anything a specialiest in Toronto put me on Cyclosporine 100mg a day cleared it up when I stopped it It came back in a couple of weeks any ideas.

  4. IanH says:


  5. IanH says:

    I proposed a while back that the mitochondrial damage is actually a depolarization which is ever changing due to the changing cytokine levels in the illness. The biggest culprit is IFN-gamma. During infection, IFN-gamma is raised, this is a normal response but if this response is prolonged the mitochondrial membrane is depolarized and will not carry out its mains functions: energy production and anti-oxidation. ROS builds up within the mitochondrion and ATP is reduced in the cytoplasm.

    In ME the cataclismic rise in IFN-gamma in the first years of the disease results in a level of IFN-gamma which will cause serious mitochondrial depolarization and the resulting exhaustion and oxidative stress. Later in the illness the causes of the symptoms are different eg. caused by reduced IL-10. Mitochondrial function will have improved but is still sub-optimal.

    This is why PQQ is so important early in the treatment of a mitochondrial myopathy, including ME and FM.

  6. Jessicakcecil says:

    I took it upon myself to treat the problem because my doctors proved to be utterly uninformed about this condition. I started taking OTC Zyrtec daily. It keeps the itchy rash away, but if I miss even one dose it returns. I don’t know if there is some other environmental factor contributing to the rash, but I am moving to a new house soon and will be discontinuing my use of Zyrtec to see if it was something in my old home. (The rash appeared shortly after we moved into that house.) I don’t know if there is a cure or some other remedy, but the Zyrtec has helped me greatly. If my dosage is off by even an hour I notice! Best of luck to you. I hope this helps.

  7. ColetteH.Stelly says:

    This article is informative and encouraging. Please keep me posted.
    It would be a great step forward just to have a test doctors can use to determine the presence of fibromyalgia in patients.

  8. GreysAnatomy says:

    Really enjoyed this paper. SKin? Always looking for another angle for Fibro. Very interested in new trials however small they are.Keep up the good work.

  9. coastal123 says:

    I had a rash in the beginning too that had been there close to 4 years. They now assume it was because I’m also hypothyroid, but they’re still just guessing.

  10. nancy58 says:

    How much CoQ10 should I be taking daily for Fibromyalgia ?

    I have had it for 12 years now along with OsteoArthritis all over, head to toe, CFS, RLS, IBS, GERD, painful lower lumbar stenosis, painful sciatica in both legs, asthma, year round allergies, skin issues (due to Fibro), heel bone spurs, you m=name it!

    And YES I have tried ALL there is out there for Fibro.(and OA) I now take several supplements and pain med to keep the pain down somewhat, but not nearly enough!!

    I will try CoQ10 also but need to know what is the max should be taken daily for Fibro.?

    Thanks for any answers!
    (One who is in pain Daily all day long!)

    1. ronald.hier@bigpond.com says:

      I would be good to be able to have some sort of test to confirm fibromyalalgia I have never heard of Mitochondrial what is it?. Is there any thing for fibro pain I have had it for 10 years & never been given anything it has brought Fatigure & depression

    2. scorpio2r says:

      I have had been fighting FM/CFS for ovr 20 years now and have finally had some success with the following treatments: Most Significant> Nerve block injections. If you can tolerate a number of needle injections at a time, once a week for 6-10 weeks at a time, I highly recommend this treatment. It has given me more relief from all of my pains, than any other treatment I have had over all of these years of suffering. Medications> Gabapentin (an anti-seizure medication) beneficial for treatment of pain associated with fibromyalgia and neuralgia, as well as restless leg, withdrawal symptoms and even headaches and hot flashes. I prefer this over Lyrica because it does not have the weight gain side effect. NOTE: This medication will cause drowsiness at first, until your systems adjusts to the increasing dosages; Cymbalta, which I actually take for depression, was the first medication of its kind (SNRI’s) which has given me the added benefit of relieving some of the pain associated with FM. By itself it did not give relief for the times when flare-ups cause widespread body pain. I would CAUTION about a significant side effect to this med. for some people (myself included)- and that is that it does have a “withdrawal factor” ie. the discontinuation-emergent side effects (headache, nausea, fatigue, dizziness, irritability, insomnia, paresthesia), though I found it to be significantly less than Effexor which I was previously taking. The worst of these were what FMers call brain “zaps” and/or “flutters”. As long as I do not skip a dose and take this medication at the same times every day, I can avoid these symptoms entirely; Mirapex, I take for restless leg. This medication was a little bit of a miracle drug for me as it is the only thing that has ever helped in treating this disorder which I have had since childhood and which had become more severe with the onset of FM/CFS. I take a muscle relaxant as needed but try to only take NSAIDS or other OTC analgesics when absolutely necessary in the instances when additional pain factors overwhelm, ie. from minor trauma/injuries, severe back pain, tooth and/or TMJ pain, and headaches). I have only recently started taking the CoQ10 and so I am not sure what, if any additional help this will give me. But I have heard a lot of positive things about it.

      As you know, we can only treat the symptoms and there is still not a cure. I definitely still have flare-ups under certain conditions, like the weather, or whenever I overdo things or am overly stressed about something. But, for the most part, overall, the above regimen is what is helping me cope and giving me back some of the quality of life I thought I had lost forever. I hope some of these will help you too!

    3. rogerlee says:

      I have had FM and ME/CFS for almost 30 years. Out of many Doctors I have had 2 I thought as experts. They both recommended for me a dose of 1800 to 2000 mg per day. I have been taking it for about 5 years, believe in it and will continue to take. Good luck Roger

  11. JulesV says:

    This is a very good article that explains how Mitochondrial work and suggested doses of COQ10 and how D-Ribose can help with energy production

  12. Jen123456 says:

    I took CoQ10 and found it really helped with my fibro fog.

    I have been completely free of my FM symptoms for nearly a year and it has been down to nutrition. I was diagnosed by a consultant rheumatologist and the condition was disabling for me. A friend suggested I watch Joe Cross’ movie Fat Sick & Nearly Dead (it’s on youtube and he has made a 2nd one since), he cured his auto-immune disease by going on a 60 day fast of home made veg & fruit juice, and then following Dr Joel Fuhrman’s nutrition diet. I got his reboot juice diet book and a juicer, then juiced for 60 days and been careful with my diet since. Joe has a free website with all the info and a community for support. I was pain free at 3 weeks but continued for the full 60 days as I ached still if I cheated on the fast. I can have gluten, dairy etc now and I’m fine but I try not to, and I still have a juice or 2 every day. Dr Fuhrman has had success with FM on his nutrition diet too, his book is Eat to Live. I hope this helps others to break free.

  13. SweetAnnaMargaret says:

    I am extremely encouraged by this / these studies. My Father had what he called “boils”, and they were so excessive and painful at times, that he was even discharged from the US Army on the specifically as a disability!
    He would have ‘flares’ that would last anywhere from 6 months to 2-3 years, where the ‘boils’ were so horribly painful, that wearing clothing hurt him. His scarring was massive too.
    I began experiencing significant ‘flares’ of these “boils” directly following my completion of a 6 moth treatment for Hepatitis C – Geno Type 3a (contracted through a blood transfusion). I was treated very aggressively with Pegalated Interferon injections (weekly), and Ribavirn (daily) By 5 weeks, the Ribavirin had severely attacked my bone marrow, and I lost the ability to generate red blood cells. During this time, I was still working a full time job as a Substance Abuse Counselor and Case Manager teaching inside jails, and working with inmates to assist in developing release plans. It was a very demanding job, with travel, and a heavy case load. My own Case Management Nurse for my HCV Treatment phoned me at work to tell me about my CBC labs (I was having blood drawn weekly to monitor me) and that my red cell count was dangerously low, and she was adding another weekly injection called “Procrit”, and that I needed to take a medical leave of absence from work, to allow my body to rest and work with the treatment.
    I began the HCV treatment feeling pretty healthy, at age 44. I knew I had underlying health ‘issues’, but I figured that if I just ‘trudged through’, and the HCV treatment team deemed me healthy enough to do this treatment, then, I must be ‘OK’, and my intense fatigue, pale skin, excessive sweating, and overall body pains and itching, were just side effects of the HCV Treatment medications.
    Within 1 week of completing the HCV Treatment, and my Red Cell Count being acceptable, I returned to work full time. About 1 week after returning to work, I started experiencing sudden intense “muscle” pain in my right arm, a searing ‘itch’ on the inside of my forearm, and a “sore”, that looked like a 3/4 circle with tiny white ‘things’ in it.
    I saw my General Practitioner for it, as the pain and itching just didn’t make sense coming from just one “sore”. I was diagnosed with Shingles, and prescribed Acyclovir and an opiate pain medication.
    The Shingles treatment seemed to work.
    The next year, about 8 months following the HCV treatment completion, and Shingles outbreak, I had gotten to a point where I had constant pains that seemed to make no sense, very intense itching, and overwhelming sweating and fatigue. I quit my job, following months of asking my boss to please hire another counselor to help with the case load and classes,..as we had the money in the budget for another staff member, and I was getting very burned out. She would say, “Hang in there Maggie. We will get you someone soon to work with you and relieve you of so much work”. Every month, I would ask, “when are we hiring another staff?”, and I would again be asked to ‘hang in there’, and so on. After a decade working in my field, and the extreme case loads I had been carrying, I just finally said “I QUIT!”
    That was in the Spring of 2005 , and by the Fall of 2008, my entire right side of my back, neck, and shoulders, were covered in sores that seemed to never heal, and were absolutely the most painful ‘health issue’ I had ever had. I had around 100 open sores .
    Since I was no longer working , I had no Health Insurance, and was seen by a Nurse Practitioner at a Community Clinic with a sliding fee scale (My husband made ”to much money” for me to qualify for any assistance, yet, our cost of living here in East San Diego County, CA – USA , was so high, that we struggled every month to make or bills, buy gas, and food.)
    I was treated with topical ointments, antibiotics of all kinds, antivirals, opiate pain medications, even medications for depression and anxiety (Elavil, *Gabapentin,..Prozac, and Trazadone) yet there was never any improvement in the pain, the sores, or my debilitating fatigue, and inability to sleep more than 20 minutes without waking to pain or itching. (*Neurontin. This made me very nauseated, so I stopped it after 4 weeks)
    After approx. 18 months of these open sores, I spontaneously began to heal! It was like a sudden miracle! I was left with a ‘cape’ of Hypopigmentation scars covering 1/3 of my back.
    I seemed to be in a “remission” of sorts. I accepted the Shingles diagnosis and dealt with the ongoing in tense pain with prescription pain medications. (Though, being sober since 9/19/91, I was concerned with the amount of medications I was on for pain, so I self referred to a Methadone/Medication Managed Treatment Program for 1 year,.. discontinuing all prescribed pain medications, and reaching a therapeutic level of Methadone that did address my pain fairly well on a consistent basis. I also thought “hmm? Maybe the pain meds created an allergy in me, not unlike Hypersensitivity Vasculitis, and I healed because I reduced and then stopped them?”
    I went just one year, actually 10 months on Methadone, peaking at 140 mg, and reducing that to 30 mg by my 8th month, and then I switched ov er to Suboxen for 2 months.. the 2 months following stopping the Suboxen were intense with insomnia, pain, depression).
    I was able to “pull up out” of this ‘episode’ of pain, sores, and medication eventually, and I went about 2 years without pain requiring more than OTC analgesics, or any ‘sores’ erupting.
    I seemed to get a “flu”, body aches, repository congestion, .but, it was also accompanied by intense itching again, and 2 weeks after I started feeling sick, (the respiratory stuff cleared up, as well as the high fevers), I again broke out with sores. If I had an ingrown hair, a nick from shaving, any break whatsoever in my skin, it bacame a “sore” that grew to the size of a pencil eraser end up to the size of a dime, some larger. Again, I was told that it was “shingles”, that I am 2% of the population of people who have had shingles, who has “reoccurring shingles”. The same medications were used/tried, and “it” went on this time for 2 years, with sores “clustering” or following in a “line” on BOTH sides of my upper back, on my buttocks, my groin area, and on one thigh.
    Again, they seemed to spontaneously begin to heal, though left me again with even more scarring, both Hypo and Hyper pigmentation..the sores below my waist turning to purple and brown scars.
    All this time, I hurt. I never ever stopped hurting whether I had sores or not.
    Recently, in the past 2 years 4 months, I again have been experiencing massive sores, and now they have ‘broken out’ on my arms and calves, in addition to My right Butt cheek,..which is the worst!! Deep, painful sores that are seeming to create SEARING pain down my leg, yet, recently (within the past month) both of my legs are in pain with what feels like fire.
    I was diagnosed with Fibromyalgia just last February 2014, and again.. medications were tried. Lyrica seemed to not help, @ 150 mg 2x’s a day, so the Nurse Practitioner double it (300 mg 2x’s a day) and within days, I was experiencing SEVERE Parkinson like side effects, ie: head bobbing, hands shaking, etc.. so the medication was completely stopped.
    I am in a Pain Mgmt. Program and being treated with Fentanyl Patches, Oxycodone, and Soma.
    I have also contracted numerous bouts with Cellulitis and Staph infections, and CA-MRSA.
    (Remember, I have no Health Ins., so I am only able to afford to treat some symptom s, etc.)
    Just recently, I was diagnosed with IDD/Immune Deficiancy Disorder, and after many rounds of treatment with Doxycycline, Septra, Keflex, and Amoxicillin … I INSISTED that I be started in a Bactrim DS 12 Month Protocol.
    I have been on the protocol for 1 week, and the sores (Now I have a “cape” of scars on my back, my right butt cheek has been so ‘debrided” that the scarring is in ‘bumps and valleys”. My arms are affected horribly, as are my calves at this time).
    I changed my wound care approach myself, by stopping topical Bacatracin, and using Ichthammol Ointment in place of it with another ointment that has 20% Benzocaine (BOTH OTC). I no longer clean them with Hydrogen Peroxide..(as I was told to do!), and use just warm soap and water and/or a Saline Solution (with antimicrobial in it)
    I HURT!!!.. I hurt Inside and outside!
    I 100% believe that my “sore” –disorder– and Fibromyalgia are directly related, and that it IS hereditary, and that I have received very very poor health care for it.
    I seem to be beginning to heal again (the open sores)…I have approximately 70 over my body, which is less that a few weeks ago, where I had over 100.
    They still itch and hurt horribly, yet I have cut my opiate pain medication in 1/2, because I am fearful of the side effects, and the dependence my system has developed to it.
    I get very depressed over all of this, I can’t even begin to list all the symptoms. My eyesight has gotten worse, I cram o easily, I have painfully intense :hot Flashes” that begin in my “core” and radiate out, peaking in an outbreak of sweating in about 10 minutes time.
    I cannot tolerate heat at all. If it is over 80 degrees, I hurt and itch more. Direct sunlight BURNS..no matter the temperature.
    … I can go, on..and on, yet I also forget much on the list of ‘things’ I experience.
    I hope that these studies result in some new therapies.
    Vasculitis, Nodular Prurigo, Shingles, Anklosing Sponditis, Fibromyalgia, Cyclothymic Dosorder, IDD, …>?????
    .. I want to know what is REALLY going on,,,..and I want some help.

    1. lin5 says:

      It seems there are many things involved in Fibro.

      Check Thyroid antibodies -even if your TSH is within range and all other thyroid tests are withing range just get your antibodies tested anyway. You might find that you have Hashimotos . If you have Hashi’s then you are gluten intolerant. There is a genetic test that can test just for that and it’s not expensive. Gluten sensitivities can lead to gut permeability and that means you are probably not getting many nutrients to your cells and organs. And guess what that means?

      Often you will find Virus’. bacteria, fungi and or yeasts.

      You might find that beside Hasimoto you have other autoimmune issues. Meaning your immune system is attacking different parts of your body inside or out.

      Learn about liver functioning and detoxing.

      Seems that one by one things start going downhill and it’s all related. For instance a low immune function can set a latent infection into action. That can in turn stimulate your immune system so much that in long time affect causes autoimmune disease.

      You must find out what is causing it. What is the root of it and then you can begin to fix it.

      In my research I found some very interesting information on Fibro written by Dr. Brice Vickery. He has been working with fibro patients for a long time. It has enlightened me so to speak. I just hate to see so much suffering.

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