By Connie Strasheim
I love licorice! Well, the candy, yes, but even more, the herb, because of how great it makes me feel! Since incorporating licorice root (Glycyrrhiza glabra) into my health regimen several years ago, I’ve experienced greater stamina, energy and overall wellbeing. This could be because licorice causes the body to retain cortisol—which is a good thing if you battle advanced adrenal fatigue and are cortisol deficient-as I typically am. Cortisol helps to regulates a multitude of functions in the body, including energy, blood pressure, blood sugar, thyroid function and inflammation, among others—so it’s important to have the right amount; not too much, but not too little, either. Having either too much or too little will cause immune dysfunction.
My morning cortisol levels have always been “in the tank” so taking a teaspoon of licorice herbal extract seems to help me get up and get going at the start of the day, and helps me to shake off any heaviness in my body from the night. Whenever I feel inflamed, it seems to “cool” my body down.
What’s more, licorice helps me to stand for long periods of time. I battle postural hypotension; meaning, my blood pressure drops whenever I stand for long periods of time. Licorice boosts the body’s aldosterone, which is a hormone that plays a role in blood pressure regulation, so by boosting my blood pressure, licorice helps me to overcome postural hypotension.
In my experience, licorice is a helpful adjunct for many people that battle chronic illnesses such as Lyme disease, chronic fatigue and fibromyalgia, because of its immune-modulating and anti-inflammatory effects. However, I wouldn’t recommend taking it long term except under your doctor’s supervision, as long term usage has been shown to cause potassium depletion. Also, because it influences blood pressure, people with cardiac and kidney conditions should consult their doctors before using it.
Licorice root is native to southern Europe and parts of Asia, and is one of the most important and widely used herbs in the world. The Chinese especially, consider it to be an herb that is key to health and it is found in more Chinese medicinal combinations than any other herb.
Adrenal fatigue expert Michael Lam, MD, states, “Licorice is a highly prized Chinese medicine. It is used in almost all of the Chinese patented herbal formulas. Licorice is the most well known herb for adrenal support. It is an anti-stress herb known to increase energy, endurance, and vitality and act as a mild tonic. Licorice is known to naturally fortify cortisone levels and it has been used to help decrease symptoms of hypoglycemia, a common side effect of decreased adrenal function. It causes increased production of aldosterone, a hormone that is frequently deficient in advanced Adrenal Fatigue.”[i] 
For adrenal-protective benefits, Dr. Lam recommends avoiding deglycyrrhized licorice (DGL),[ii]  which is made by removing the glycyrrhizin, a compound in the licorice. Instead, he recommends taking pure herbal extracts.
Licorice contains over 200 compounds, many of which have been shown in studies to have broad-spectrum medicinal properties. For instance, a study review of 93 papers published in Pharmaceutical Biology in December 2017 states, “ Licorice extract, 3 triterpenes and 13 flavonoids exhibit evident anti-inflammatory properties mainly by decreasing TNF, MMPs, PGE2 and free radicals, which also explain its traditional applications in stimulating digestive system functions, eliminating phlegm, relieving coughing, nourishing qi (or the body’s vital force) and alleviating pain in TCM.”[iii] 
Indeed, many studies have shown it to have anti-inflammatory, antimicrobial, antioxidant, and immune regulating properties, in addition to liver, adrenal and heart strengthening properties.[iv] [v] 
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It has been used worldwide treat a wide variety of conditions, including, but not limited to, gastrointestinal and liver disorders, diabetes, chronic fatigue syndrome, menopausal symptoms, lupus, malaria, high potassium levels in the blood, food poisoning, and bacterial and viral infections. Studies show it also has anti-cancer properties.
Licorice comes in many forms; as an whole herb, powder, liquid extract, capsule, tea, and so on. Recommended dosages depend upon the individual, so if you are considering taking it, ask your doctor whether it’s an appropriate remedy for you, and if so, how much you can take. Indeed, licorice can be a valuable supportive remedy for people with Lyme disease, chronic fatigue syndrome, fibromyalgia and other inflammatory conditions, but like all things, it isn’t for everyone. Short-term use of the herb is safe for many people, but again, you’ll want to ask your doctor whether it may benefit you.
In any case, it is one of my go-to staples for wellness; one I look forward to taking every morning as a tincture in my energy drink, and one which helps me to face the day with joy , energy and positive expectation!
Further Reading and References
[i]  Lam, M. Adrenal Support Supplements: A Guide to Safe and Effective Use. Dr.Lam.com. Accessed on June 14, 2018 from: https://www.drlam.com/blog/adrenal-support-supplements/7549/ .
[ii]  Lam, M. Adrenal Support Supplements: A Guide to Safe and Effective Use. Dr.Lam.com. Accessed on June 14, 2018 from: https://www.drlam.com/blog/adrenal-support-supplements/7549/ .
[iii]  Yang R1, Yuan BC1, Ma YS1, Zhou S1, Liu Y1. The anti-inflammatory activity of licorice, a widely used Chinese herb. Pharm Biol. 2017 Dec;55(1):5-18. Epub 2016 Sep 21.
[iv]  Hussain H1,2, Green IR3, Shamraiz U4, Saleem M5, Badshah A4, Abbas G6, Rehman NU2, Irshad M7. Therapeutic potential of glycyrrhetinic acids: a patent review (2010-2017). Expert Opin Ther Pat. 2018 May;28(5):383-398. doi: 10.1080/13543776.2018.1455828. Epub 2018 Mar 26.
[v]  Ojha SK1, Sharma C1, Golechha MJ1, Bhatia J1, Kumari S2, Arya DS3. Licorice treatment prevents oxidative stress, restores cardiac function, and salvages myocardium in rat model of myocardial injury. Toxicol Ind Health. 2015 Feb;31(2):140-52. doi: 10.1177/0748233713491800. Epub 2013 Jun 14.
Connie Strasheim is the author or co-author of 11 wellness books, including the recently released New Paradigms in Lyme Disease Treatment: 10 Top Doctors Real Healing Strategies that Work . (October, 2016) and Beyond a Glass of Milk and a Hot Bath: Advanced Sleep Solutions for People with Chronic Insomnia. (March, 2017). She is also a medical copywriter and an editor at ProHealth.com, as well as Editor of the Alternative Cancer Research Institute (ACRI). Her passion is to help people with complex chronic illnesses find freedom from disease and soul-spirit sickness using whole body medicine, and she collaborates with some of the world’s best integrative doctors to do this. In addition to Lyme disease and insomnia, Connie’s books focus on cancer, nutrition, detoxification and spiritual healing. To learn more about her work, see: www.ConnieStrasheim.org.