Long-Term Treatment with a Staphylococcus Toxoid Vaccine in Patients with Fibromyalgia and Chronic Fatigue Syndrome – Source: Journal of Chronic Fatigue Syndrome, Vol 13 #4, 2007

One hundred and sixty patients with Fibromyalgia and Chronic Fatigue Syndrome, who were on a continuous treatment with a Staphylococcus vaccine, were followed during one year with repeated consultation visits.

The patients had participated in controlled studies and been on continuous treatment with the vaccine for 22 ±10 months before inclusion into this follow-up study. They were treated with 1 mL of the vaccine subcutaneously every third to fourth week.

Adverse events were few. The adherence to the treatment was very good.

Over a period of one year, 8% withdrew, and in only 5%, the withdrawal was due to insufficient clinical effect. Only in two cases, where the patients were allergic to the preservative of the vaccine, the side effects caused the withdrawal of the treatment.

Ratings with scales (CPRS-15 and FibroFatigue) showed improvement from start of treatment and also further improvement during the follow-up year.

In view of the natural history for these disorders the result is of interest.

Source: Journal of Chronic Fatigue Syndrome. 2007 Vol 13 #4, pp 29-40. DOI: 10.1300/J092v13n04_04, by Gottfries CG, Hager O, Regland B, Zachrisson O. Institute of Clinical Neuroscience, University of Gothenburg, Sahlgren University Hospital, Molndal, Sweden. [E-mail: carl-gerhard.gottfries.vgregion.se ]

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