OBJECTIVE: To evaluate the secretion of growth hormone in
patients with fibromyalgia (FM).
METHODS: Serum concentrations
of growth hormone (24 h profiles), insulin-like growth factor
I (IGF), and IGF binding protein-3 were determined in 10 women
with FM and in 10 healthy controls. Quality of sleep was
assessed by means of a visual analog scale.
RESULTS: Sleep was
significantly more disturbed in the patients than in controls.
A significantly lower secretion of growth hormone was found in
the patients in comparison with healthy controls.
These results suggest that growth hormone secretion is
decreased in patients with FM. Substitution therapy with low
doses of growth hormone may be worth evaluating in the
treatment of FM.
Bagge E, Bengtsson BA, Carlsson L, Carlsson J