10% Off $75 Orders! Use Code SAVE10P Shop Now
One use per customer. Not available with Autoship. Expires 5/28/18.

Lyme arthritis. Spirochetes found in synovial microangiopathic lesions.

1 Star2 Stars3 Stars4 Stars5 Stars (No Ratings Yet)
Loading...

Abstract

In 17 patients with
Lyme disease, synovial specimens, obtained by synovectomy or needle biopsy, showed nonspecific villous hypertrophy, synovial cell hyperplasia, prominent microvasculature, lymphoplasmacellular infiltration, and sometimes lymphoid follicles. The larger surgically obtained specimens also showed striking deposition of fibrin in synovial stroma and a form of endarteritis obliterans. In 2 patients, spirochetes were seen in and around blood vessels by the Dieterle silver stain. Compared with 55 cases of other synovial
disease, obliterative microvascular lesions were seen only in
Lyme synovia, but marked stromal deposition of fibrin seemed nonspecific. These findings imply that the
Lyme spirochete may survive for years in affected synovium and may be directly responsible for the microvascular injury.

Am J Pathol. 1985 Jan;118(1):26-34. Research Support, Non-U.S. Gov’t; Research Support, U.S. Gov’t, P.H.S.

1 Star2 Stars3 Stars4 Stars5 Stars (No Ratings Yet)
Loading...



Leave a Reply