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In Europe the tick-transmitted neurologic disorders MPN-GBB or Bannwarth’s syndrome and ACA-associated neuropathy have been identified as clinical entities long before their causative agent was discovered. When
Lyme disease and its neurologic manifestations were recognized in the United States, differences in the clinical pattern between North American and European cases with
Lyme borreliosis were described in the initial reports. In the same way with the availability of serodiagnostic tests as the clinical spectrum of
Lyme borreliosis was enlarging in Europe and in North America, these clinical differences became less prominent.