To review the presentation, treatment, and prevention of
Lyme disease in primary care.
Selected articles from the scientific literature and the Centers for
Lyme disease is a tick-borne, multisystem inflammatory
disease with worldwide distribution caused by the spirochete Borrelia burgdorferi.
Lyme disease is initially characterized by a spreading, annular erythema migrans skin rash and can disseminate to the musculoskeletal, neurologic, or cardiovascular system. Stages of the
disease present with varying clinical manifestations.
IMPLICATIONS FOR PRACTICE:
Lyme disease with appropriate antimicrobial therapy should be prompt in order to avoid debilitating outcomes. Awareness of the many presentations of
Lyme disease in endemic areas may facilitate a timely diagnosis and appropriate treatment.