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Increased intracranial pressure in patients with
Lyme disease is an uncommon but reported finding. We discuss 2 patients from
Lyme endemic areas who initially presented with headache, nausea, and vomiting and were eventually found to have increased intracranial pressure, a mild cerebrospinal fluid pleocytosis, and positive
Lyme titers. It has been shown that increased intracranial pressure in association with neuroborreliosis can lead to blindness. In endemic areas, it is important for practitioners to consider
Lyme disease when patients present with persistent headache, especially in those who have evidence of increased intracranial pressure.