Magnesium deficit in a sample of the Belgian population presenting with chronic fatigue

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97 patients (25 per cent males, ages ranging from 14 to 73 years,
median 38 years) with complaints of chronic fatigue (chronic
fatigue syndrome, fibromyalgia or/and spasmophilia) have been
enrolled in a prospective study to evaluate the Mg status and
the dietary intake of Mg. An IV loading test (performed
following the Ryzen protocol) showed a Mg deficit in 44
patients. After Mg supplementation in 24 patients, the loading
test showed a significant decrease (p = 0.0018) in Mg
retention. Mean values of serum Mg, red blood cell Mg and
magnesuria showed no significant difference between patients
with or without Mg deficiency. No association was found
between Mg deficiency, CFS or FM. However serum Mg level was
significantly lower in the patients with spasmophilia than in
the other patients.

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