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Magnesium supplementation improves glycemic response in diabetics

Magnesium supplementation reduces insulin resistance and improves the glycemic control indicators among type 2 diabetic patients
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Reprinted with the kind permission of Life Extension.

January 02 2019. The outcome of a trial reported on December 26, 2018 in Nutrients revealed improvements in glycemic response in association with supplementation with magnesium among patients with diabetes.

The trial included 42 type 2 diabetics between the ages of 35 to 60 years of age who received 250 milligrams per day elemental magnesium or no supplementation for three months. The composition of the two groups did not significantly differ in regard to age, gender, fasting blood glucose and magnesium levels. Blood samples collected before and after the treatment period were analyzed for fasting blood glucose, fasting insulin, fasting C-peptide (which evaluates insulin made by the body), hemoglobin A1c, and serum calcium and magnesium levels. Participants were instructed to consume a healthy diet that was high in fruit, vegetables, legumes, nuts and whole grains throughout the course of the study.

At the end of the trial, serum calcium levels were lower and magnesium levels were higher among participants who were given magnesium compared to the untreated control group, which resulted in a reduction of the calcium to magnesium ratio. Insulin, hemoglobin A1c, C-peptide and insulin resistance decreased significantly in the group that supplemented with magnesium in comparison with the controls. While fasting blood glucose increased by an average of 10.1 milligrams per deciliter (mg/dL) in the control group, it declined by an average of 10.55 mg/dL in magnesium-supplemented subjects.

“The results of this study revealed that oral magnesium supplementation reduces insulin resistance and improves the glycemic control indicators among type 2 diabetic patients,” authors Wafaa A. ELDerawi and colleagues conclude.

They note that “The differences in the results of the previous clinical trials, which investigated the effectiveness of magnesium supplements on glycemic control indicators, could be explained by the differences in the magnesium dosages and the duration of supplementation.”

—D Dye

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