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The incidence and variety of diseases associated with tick bites have continued to grow worldwide.
Lyme disease, the most common tick-borne
disease in the United States, has received extensive media coverage because of its protean manifestations and propensity for causing chronic
disease. Our ability to prevent, identify, and effectively treat
Lyme disease and other tick-borne diseases has significantly improved in the last decade. Tick-borne illnesses should be one of the differential diagnostic considerations in patients with consistent clinical findings and exposure history. In addition, the prudent use of laboratory testing ensures an accurate diagnosis while avoiding the cost and risk of inappropriate diagnostic tests and antibiotic therapy.