Measuring the functional impact of fatigue: initial validation of the fatigue impact scale

The fatigue impact scale (FIS) was developed to improve our

understanding of the effects of fatigue on quality of life.

The FIS examines patients’ perceptions of the functional

limitations that fatigue has caused over the past month. FIS

items reflect perceived impact on cognitive, physical, and

psychosocial functioning. This study compared 145 patients

referred for investigation of chronic fatigue (ChF) with 105

patients with multiple sclerosis (MS) and 34 patients with

mild hypertension (HT). Internal consistency for the FIS and

its three subscales was > .87 for all analyses. Fatigue impact

was highest for the ChF group although the MS group’s reported

fatigue also exceeded that of the HT group. Discriminant

function analysis correctly classified 80.0% of the ChF group

and 78.1% of the MS group when these groups were compared.

This initial validation study indicates that the FIS has

considerable merit as a measure of patient’s attribution of

functional limitations to symptoms of fatigue.

Fisk JD, Ritvo PG, Ross L, Haase DA, Marrie TJ, Schlech WF

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