MMPI profiles of patients with Chronic Fatigue Syndrome (CFS)

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Fifty-three patients with chronic fatigue syndrome (CFS) and 43
healthy nonpatient controls completed the Minnesota
Multiphasic Personality Inventory (MMPI). All subjects varied
in their degree of seropositivity to active Epstein-Barr virus
(EBV) as measured by their anti-early antigen titers. EBV
titers were higher among CFS patients and were associated with
being more symptomatic. Differences in patient status were
associated with statistically significant elevations on 8 of 9
clinical scales, 4 of which also showed clinically significant
elevations (T scores > or = 70): scales 1, 2, 3, and 8. These
results are discussed in terms of their implications for
intervention strategies associated with MMPI-based CFS
subtypes.

Schmaling KB, Jones JF