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Molecular mimicry: a critical look at exemplary instances in human diseases.

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Abstract

Molecular mimicry, the concept that antigenic determinants of microorganisms resemble antigenic determinants of the host, is frequently cited as a plausible mechanism to account for the association of infection and autoimmune
disease. Based on analogous sequences of amino acids or on cross-reactions of monoclonal antibodies, numerous examples of such mimicry have been reported. There are, however, no clear examples of a human
disease caused by molecular mimicry.

Cell Mol Life Sci. 2000 Apr;57(4):542-51. Research Support, U.S. Gov’t, P.H.S.; Review

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