Neurally mediated hypotension & Chronic Fatigue Syndrome (CFS)

A substantial body of clinical evidence now supports an

association between various forms of hypotension and both

idiopathic chronic fatigue and the chronic fatigue syndrome

(CFS). Patients with CFS have a high prevalence of neurally

mediated hypotension, and open treatment of this autonomic

dysfunction has been associated with improvements in CFS

symptoms. Randomized trials are now in progress to evaluate

the efficacy of treatments directed at neurally mediated

hypotension in those with CFS patients, and the results of

these trials should help guide more basic inquiries into the

mechanisms of orthostatic intolerance in affected individuals.

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