Omega-3 fatty acids may help nerves resist or recover from injury, UK studies suggest

Studies by neuroscientists at Queen Mary, University of London suggest that omega-3 fatty acids, which are found in fish and krill oil, have the potential to protect nerves from injury and help them to regenerate.

When nerves are damaged because of an accident or injury, patients experience pain, weakness and muscle paralysis, which can leave them disabled, and recovery rates are poor.

The new study, published Jan 11 by the Journal of Neuroscience, suggests that omega-3 fatty acids could play a significant role in speeding recovery from nerve injury.

The study focused on peripheral nerve cells. Peripheral nerves are the nerves which transmit signals between the brain & spinal cord and the rest of the body. These nerves have the ability to regenerate but, despite advances in surgical techniques, patients usually only have good recovery when their injury is minor.

Omega-3 fatty acids are vital for the body’s normal growth and development, and have been widely researched for their health benefits. Because the body cannot manufacture omega-3 fatty acids, they have to be consumed in foods such as oily fish or fish oil supplements. Or oil from krill (where the fish get it).

In the new study, researchers first looked at isolated mouse nerve cells.

They simulated the type of damage caused by accident or injury, by either stretching the cells or starving them of oxygen. Both types of damage killed a significant number of nerve cells, but enrichment with omega-3 fatty acids in cells gave them significant protection and decreased cell death.

Next the researchers studied the sciatic nerves of mice.

The sciatic nerve, which runs from the lower back down through the buttock and back of the leg, is the source of a very common and painful condition (sciatica) in humans – caused by pressure, inflammation, or injury of the nerve.

The team found that a high level of omega-3 fatty acids helped mice to recover from sciatic nerve injury more quickly and more fully, and that their muscles were less likely to waste following nerve damage.

According to lead researcher Adina Michael-Titus, Professor of Neuroscience:

“Our previous research has shown that these fatty acids could have beneficial effects in a number of neurological conditions. This new study suggests that they could also have a role in treating peripheral nerve injuries. More work is needed but our research indicates that omega-3 fatty acids can protect damaged nerve cells, which is a critical first step in a successful neurological recovery.”

Source: Queen Mary, University of London news release, Jan 11, 2012

1 Star2 Stars3 Stars4 Stars5 Stars (18 votes, average: 3.90 out of 5)

Leave a Reply