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Lyme disease is a multi-system organ
disease caused by Borrelia burgdorferi. Although ocular manifestations have been reported, these remain a rare feature of the
disease. To our knowledge, the radiology literature has not documented orbital
Lyme disease both before and after treatment. We present the MR imaging findings of florid
Lyme disease affecting the extraocular muscles in a 46-year-old man. A follow-up MR imaging study performed 6 months after a course of antibiotic therapy revealed complete resolution of the myositic changes.