PACE trial claims for recovery in myalgic encephalomyelitis/chronic fatigue syndrome – true or false? It’s time for an independent review of the methodology and results

By C.B. Shepherd
 
Abstract
 
The PACE trial set out to discover whether cognitive behaviour therapy and graded exercise therapy are safe and effective forms of treatment for myalgic encephalomyelitis/chronic fatigue syndrome. It concluded that these interventions could even result in recovery. However, patient evidence has repeatedly found that cognitive behaviour therapy is ineffective and graded exercise therapy can make the condition worse. The PACE trial methodology has been heavily criticised by clinicians, academics and patients. A re-analysis of the data has cast serious doubts on the recovery rates being claimed. The trust of patients has been lost. The medical profession must start listening to people with myalgic encephalomyelitis/chronic fatigue syndrome if trust is going to be restored.

Source: Shepherd CB. PACE trial claims for recovery in myalgic encephalomyelitis/chronic fatigue syndrome – true or false? It’s time for an independent review of the methodology and results. J Health Psychol. 2017 Aug;22(9):1187-1191. doi: 10.1177/1359105317703786. Epub 2017 Apr 9.

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One thought on “PACE trial claims for recovery in myalgic encephalomyelitis/chronic fatigue syndrome – true or false? It’s time for an independent review of the methodology and results”

  1. siebertesther says:

    Hi and thanks for all you do! I’ve noticed recently that many of your articles I see headlines for on Google News are like this one. I would prefer to see declarative headlines, not questions, if you are, as I assume, an advocacy organization set up to help patients. I think most people don’t read these articles and just skim the headlines and what that headline says is that the PACE study’s validity is still in question. Not sure of the location of your readers though but most of us in the US think PACE research has been thoroughly debunked. This headline implies it is still under debate which may be right if your readers are in England. Just a thought… Best, Esther

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