Percent positive rate of Lyme real-time polymerase chain reaction in blood, cerebrospinal fluid, synovial fluid, and tissue – Source: Diagnostic Microbiology and Infectious Disease, Oct 21 2008

We performed a retrospective review of 23,777 specimens tested by our Lyme real-time polymerase chain reaction assay to determine the percent positive rates by specimen source. The percent positive rates were:

• Highest in synovial fluid [lubricant within joints] (6.4%) and tissue (6.5%),

• And lowest in blood (0.1%) and cerebrospinal fluid (0.09%).

Source: Diagnostic Microbiology and Infectious Disease, Oct 21 2008, E-pub ahead of print. PMID: 18947959 by Babady NE, Sloan LM, Vetter EA, Patel R, Binnicker MJ. Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA. [E-mail: binnicker.matthew@mayo.edu]

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