FREE U.S. Shipping on $75+ Orders

Serologic diagnosis of Lyme disease.

1 Star2 Stars3 Stars4 Stars5 Stars (No Ratings Yet)
Loading...

Abstract

Indirect fluorescent antibody tests and enzyme-linked immunosorbent assays are being used as laboratory aids for the diagnosis of
Lyme disease and related disorders. Depending on the needs, polyvalent or class-specific reagents can be used to detect total immunoglobulins (Ig) or IgM and IgG antibodies. The sensitivities of these assays are relatively low when serum samples are obtained from patients within 3 weeks after onset of erythema migrans and are tested by either the IFA method or ELISA. During neuritis or arthritis, IgG antibody levels are usually elevated, and serologic verification is more easily achieved. Cross-reactivity occurs when sera from patients with
Lyme disease, relapsing fever, or treponemal infections are screened against heterologous antigens, but these diseases can usually be separated clinically or by further seroanalyses. Although IFA tests and ELISA are both suitable for confirming
Lyme disease, the objective results and the ability to perform many more analyses make ELISA the preferred method.

Ann N Y Acad Sci. 1988;539:154-61. Review

ProHealth CBD Store

 

Are you vitamin d deficient?

1 Star2 Stars3 Stars4 Stars5 Stars (No Ratings Yet)
Loading...



Leave a Reply