“Silicone related symptoms” are common in patients with fibromyalgia (FM): no evidence for a new disease’

OBJECTIVE: To ascertain if the symptom content and rate of
symptoms in patients with fibromyalgia (FM) are similar to
those in what has been called silicone implant associated
syndrome (SIAS), and to determine if SIAS is indeed a new
disease or whether it is largely recognizable as FM.

Mailed survey to 901 patients in Wichita, KS, Portland, OR,
Los Angeles, CA, Peoria, IL, Boston, MA, San Antonio, TX, and
eastern Kansas who were participating in a longterm outcome
study of FM. Laboratory data were available from Wichita

RESULTS: Content of symptoms was similar to that in
SIAS, and rates were generally as high or higher in patients
with FM than in SIAS. In patients with FM, 37.2% had all of
the following 5 items: arthralgias, myalgias, sicca complex,
atypical rash, and symptoms of a peripheral neuropathy; and
55.2% had 4 of the 5 items.

CONCLUSION: These data do not
suggest that SIAS is an unrecognized new disease, but suggest
the opposite, that such symptoms are well known and previously
recognized, and are common among those with musculoskeletal
complaints and those seen in rheumatology clinics.

Wolfe F

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