Since I was first diagnosed  with Lyme disease 13 years ago, doctors have been continually coming up with better, more comprehensive ways to treat Lyme disease. So far, no treatment has proven to be curative, although some have put some Lyme disease sufferers into remission, especially when combined with a strong supportive protocol that addresses healing the foundation, or “terrain” of the body, and not just eliminating microbes.
10-Pass Ozone and Lyme Disease
One Lyme disease treatment that has become popular of late is 10-pass ozone, a very potent and intensive type of ozone therapy that apparently goes deeper into the body and is more effective at eliminating Lyme disease pathogens than standard intravenous ozone. It was created by an Austrian gynecologist named Dr. Johann Lahodny, and it is also called the Lahodny or Zotzmann method, or Ozone High Dose Therapy.
Ten-pass ozone therapy resembles a treatment called Major Autohemotherapy (MAH), with some important differences. In both MAH and 10-pass ozone, blood is drawn from the patient and mixed with ozone, which has the effect of killing microbes and cleansing the blood. The blood is then reinserted back into the patient. One type of MAH, called Hyperbaric MAH, involves filling up a bottle with 200-220 ml of the patient’s blood, and then creating hyperbaric-like pressure inside of the bottle. Then, ozone is added and the mixture of blood and ozone are vigorously shaken to increase ozone (or oxygen, since ozone becomes oxygen in the body)– absorption into the cells. The hyperbaric pressure protects the red blood cells from damage during the process.
One 10-pass treatment is about the equivalent of ten hyperbaric MAH treatments, but is different from MAH in that it uses higher concentrations of ozone. The blood draw-infusion process is done ten times; hence the term “10 pass” and takes 1-2 hours. The amount of ozone supplied to the body is about 140,000 ug, and heparin is given to the patient to keep the blood from coagulating. By comparison, a hyperbaric Major Autohemotherapy (MAH) provides about 6,000 ug of ozone, and a regular ozone IV only 3,000 ug of ozone. This means that ten-pass ozone supplies nearly 50 times the amount of ozone of a regular intravenous ozone treatment.
In summary, because the 10-pass method of ozone administration provides a greater amount of ozone to the body, in a shorter amount of time, it better saturates the red blood cells with oxygen, which allows it to penetrate deeper and greater areas of the body. Some practitioners, such as Peter Jovanovic PhD, (Hon.), MD, Founder and CEO of Ozone Research Group Inc. contend that it can even eliminate cyst forms of the Lyme disease organism, the main causative agent of Lyme disease relapses.
Dr. Lahodny, the developer of the ten-pass method, recommends up to daily administrations of high dose ozone for up to a month for certain diseases. However, a person who is highly infected with Lyme disease organisms may not be able to tolerate this much therapy. Some other practitioners may give their patients as little as one treatment per week. So far, anecdotal reports from patients and practitioners indicate that those that have gone into remission from high dose ozone therapy have needed anywhere from about 10-30 treatments.
The main disadvantage of 10-pass ozone is its price. At around $1,000 for one treatment, many people with Lyme disease may not be able to afford it. A few practitioners may charge as little as $500 per treatment, and a few clinics overseas are less expensive. Amazingly, Dr. Lahodny charges only about 100 Euro at his clinic in Austria, although patients from the United States and other countries may yet find the expense of travel to another country to do the treatment, to be less than what the treatments would cost at home.
Doctors have been using ozone therapy for years, but 10-pass ozone takes ozone treatment to a whole new level. However, as it has only been used in the United States for a short period of time—perhaps two years, at most, there is still not enough research or anecdotal evidence to know what the long-term, 10-pass ozone benefits or side effects will be for Lyme patients.
How to Find a Practitioner
As no clinical trials or long-term studies have been done on 10-pass ozone and Lyme disease, those who are interested in doing it will need to rely upon anecdotal evidence from doctors and patients who have tried it, for more information. Ozone may be safer and more effective than other more popular treatments that are out there, including long-term antibiotic therapy and even herbal remedies . Granted, healing isn’t just about eliminating microbes, but restoring the whole body, so doing the right antimicrobial treatment, in and of itself, isn’t likely to be sufficient for most people anyway—but doing a highly effective antimicrobial treatment- which 10-pass ozone may prove to be- can sure help to shorten the treatment runway for most.
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On Facebook groups such as Ozone To Health,  patients share their experiences with 10-pass ozone and other ozone therapies. Robert Rowen, MD, who has been doing oxidative therapies for years, also shares some of his patients’ testimonials of healing using ozone therapy on his You Tube channel : David Minkoff, MD, who is featured in my 2016 book, New Paradigms in Lyme Disease Treatment , also uses ozone to treat his Lyme disease patients and has apparently had remarkable outcomes when he has combined ozone treatment with other strong, supportive modalities  to heal the body.
To find a practitioner who does 10-pass ozone, you may want to consult the American Academy of Ozonotherapy website , which contains a list of practitioners who do ozone treatment. Not all, or even most of these practitioners, are likely to do 10-pass ozone, but as it gains popularity in the US, you may find that more do. Another way to find a practitioner who does 10-pass ozone is to simply do an Internet search using the terms “10-pass ozone” and then input your city and state into the search box.
I am excited about the potential of this therapy and look forward to learning about more Lyme disease patients’ experiences with it, as time goes on. Indeed, more conventional Lyme treatments, such as long-term antibiotics and herbal remedies, don’t always work for everyone, so 10-pass ozone may provide a better answer for some Lyme sufferers who continue to struggle in their recovery .
This article was first published on ProHealth.com on October 14, 2017 and was updated on April 11, 2019.
Connie Strasheim is the author or co-author of 11 wellness books, including the recently released New Paradigms in Lyme Disease Treatment: 10 Top Doctors Real Healing Strategies that Work. (October, 2016) and Beyond a Glass of Milk and a Hot Bath: Advanced Sleep Solutions for People with Chronic Insomnia. (March, 2017). She is also a medical copywriter and an editor at ProHealth.com, as well as Editor of the Alternative Cancer Research Institute (ACRI). Her passion is to help people with complex chronic illnesses find freedom from disease and soul-spirit sickness using whole body medicine, and she collaborates with some of the world’s best integrative doctors to do this. In addition to Lyme disease and insomnia, Connie’s books focus on cancer, nutrition, detoxification and spiritual healing. To learn more about her work, see: www.ConnieStrasheim.org. 
Further Reading and References
Jovanovic, P. The Controversial World of Medical Ozone Therapy Use. Accessed on October 3, 2017 from: http://ozoneuniversity.blogspot.com/2012/12/medical-ozone-therapy-and-lyme-disease.html .
Jovanovic, P. Medical Ozone Therapy. Accessed on October 4, 2017 from: https://medicalozone.info/ozone-therapy-contact-html/ 
What is the Ozone High Dose (10 Pass) method? ThePowerofOzone.com. Accessed on October 3, 0217 from: http://thepowerofozone.com/ozone-high-dose-10-pass/ .
Does the Ozone High Dose cure Lyme disease? ThePowerofOzone.com. Accessed on October 3, 0217 from: http://thepowerofozone.com/ozone-high-dose-cure-lyme-disease/# .
Ozone: The Power of 10 Pass (A New Treatment). Institute for Progressive Medicine. Accessed on October 4, 2017 from: https://www.iprogressivemed.com/ozone-the-power-of-10-pass-a-new-treatment/