The Frequency of Primary Sjogren’s Syndrome and Fibromyalgia in Irritable Bowel Syndrome.

To determine the frequency of sicca complex, Sjogren's Syndrome (SS) and Fibromyalgia (FM) in patients with Irritable Bowel Syndrome (IBS).
Seventy-seven IBS patients who fulfilled the Rome-III criteria were included in the study. All patients were assessed for FM according to the American College of Rheumatology (ACR) 2010 criteria. After examination for objective evidence of sicca complex by Schirmer test, TBUT and Ocular Staining Score (OSS), serological tests were performed. And the diagnosis of SS was made according to the American College of Rheumatology (ACR) classification criteria for SS – 2012.
Thirteen (16.9%) of IBS patients had FM. Dry eye was detected in 20 (26.0%), 7 (9.1%) and 29 (37.7%) patients by OSS, Schirmer test and TBUT, respectively. Of 77 patients with IBS, the diagnosis of SS was established in two patients (2.6%).
The frequency of Sjogren's Syndrome among patients with IBS is relatively higher than the general population. All IBS patients should be questioned for dryness of the mouth and eyes, and if necessary, should be evaluated for SS.
Full text available here.
Source:  Erbasan F, Cekin Y, Coban DT, Karasu U, Suren D, Cekin AH. The Frequency of Primary Sjogren's Syndrome and Fibromyalgia in Irritable Bowel Syndrome. Pak J Med Sci. 2017 Jan-Feb;33(1):137-141. doi: 10.12669/pjms.331.11168.

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2 thoughts on “The Frequency of Primary Sjogren’s Syndrome and Fibromyalgia in Irritable Bowel Syndrome.”

  1. TerryPro says:

    I had no idea that dry eye was associated with an illness. My husband suffers from ME/CFS and we think also Fybro and Prostratis and is aged 64 and always has dry eyes. I buy Hypremalose from Boots Chemists but having read this I think he might need to let his GP know about it. We just thought it was an atmospheric thing – he is househound due to his pains, we just thought it was the dry air in the house. Thank you for bringing this to my attention, although it is another ‘nail in his coffin’ so to speak.

    1. IanH says:

      You did not mention your husband’s meds.
      Amitriptyline can cause dry eyes as well as dry mouth.
      Also SSRIs can also cause dry eyes.
      In addition other medication that is used can cause dryness of mouth and eyes eg cyclobenzaprine or orphenadrine.

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